C12orf5 polyclonal antibody
产品名称： C12orf5 polyclonal antibody
英文名称： C12orf5 polyclonal antibody
产品编号： PAB13249
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of C12orf5.
- Immunogen:
- A synthetic peptide corresponding to internal region 18 amino acids of human C12orf5.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The regulation of energy generating metabolic pathways by p53.
Corcoran CA, Huang Y, Sheikh MS.Cancer Biol Ther. 2006 Dec;5(12):1610-3. Epub 2006 Dec 26.
- 2.
- Role of Wnt10b and C/EBPalpha in spontaneous adipogenesis of 243 cells.
Bennett CN, Hodge CL, MacDougald OA, Schwartz J.Biochem Biophys Res Commun. 2003 Feb 28;302(1):12-6.
- 3.
- TP53: a key gene in human cancer.
Guimaraes DP, Hainaut P.Biochimie. 2002 Jan;84(1):83-93.
- Entrez GeneID:
- 57103
- Protein Accession#:
- NP_065108
- Gene Name:
- C12orf5
- Gene Alias:
- TIGAR
- Gene Description:
- chromosome 12 open reading frame 5
- Omim ID:
- 610775
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq
- Other Designations:
- TP53-induced glycolysis and apoptosis regulator,transactivated by NS3TP2 protein